Basic Information
VIS ID
TVIS44022297
Fusion event
HTLV-1-OTOP1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p16.3
Reference genome
GRCh37/hg19
Start
4196398/4194671 (Hg38)
End
4196398/4194671 (Hg38)
Orient
+
Location type
Intronic
Target gene
OTOP1
Nearest miRNA
hsa-mir-4800/Upstream/1944515; hsa-mir-12113/Downstream/1728604;
Nearest TSS
ENST00000502981/Upstream/428273; ENST00000502918/Downstream/32218;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/50731, chr4-CpG: 138/Downstream/31701
Upstream sequence
aagggaccttcccaactttgcgttcttagggtgatatcaaaagctgcaggccctgtatgcaccatcTGAAATTCAGGGGAGGAAGCCCAAAAGCCTCTGA
Downstream sequence
GCTGCTAGGGCAACAGAGAGCAGGCTTGATAACGGAGGCTGGTAGCAAAGAGCTGACTTCACCCAGAGTGATGGGCAGGCACCTCTGTGGACTGGGGCAC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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