Basic Information
VIS ID
TVIS44022319
Fusion event
HTLV-1-chr4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
59560503/58694338 (Hg38)
End
59560503/58694338 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA4B
Nearest miRNA
hsa-mir-12113/Upstream/5981591; hsa-mir-1243/Downstream/2228281;
Nearest TSS
ENST00000502981/Upstream/129216; ENST00000513836/Downstream/282759;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/1498389, chr4-CpG: 222/Downstream/2505827
Upstream sequence
gcctggtacacagagagtgttatctttatagatagaaaatcctaaagactccaccaaattgataaatgaattcagcaaagttgcaagaaacacaagcaag
Downstream sequence
atatggaaatcagtaacacttttatatgccaacagctaaaaatctgaaaaagaaatcaagaaagcaatcccatttacaatagttgcaaaaagatgaagtc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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