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TVIS44022332
Basic Information
VIS ID
TVIS44022332
Fusion event
HTLV-1-SORCS2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p16.1
Reference genome
GRCh37/hg19
Start
7379141/7377414 (Hg38)
End
7379141/7377414 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA4A
Target gene
SORCS2
miRNAs that regulate target gene
hsa-mir-1274b
;
hsa-mir-23b-3p
;
hsa-mir-6818-5p
;
hsa-mir-1273e
;
hsa-mir-636
;
hsa-mir-520f-3p
;
hsa-mir-302c-3p
;
hsa-mir-520e
;
hsa-mir-520d-3p
;
hsa-mir-520c-3p
;
hsa-mir-520b
;
hsa-mir-520a-3p
;
hsa-mir-373-3p
;
hsa-mir-372-3p
;
hsa-mir-302e
;
hsa-mir-302d-3p
;
hsa-mir-302b-3p
;
hsa-mir-302a-3p
;
hsa-mir-93-5p
;
hsa-mir-526b-3p
;
hsa-mir-519d-3p
;
hsa-mir-20b-5p
;
hsa-mir-20a-5p
;
hsa-mir-17-5p
;
hsa-mir-106b-5p
;
hsa-mir-106a-5p
;
hsa-mir-766-5p
;
hsa-mir-873-5p
;
hsa-mir-205-3p
;
hsa-mir-141-5p
;
hsa-mir-6891-5p
;
hsa-mir-3173-3p
;
hsa-mir-7111-5p
;
hsa-mir-548l
;
hsa-mir-6870-5p
;
hsa-mir-5698
;
hsa-mir-4723-5p
;
hsa-mir-6825-5p
;
hsa-mir-7106-5p
;
hsa-mir-6797-5p
;
hsa-mir-1249-5p
;
hsa-mir-765
;
hsa-mir-6133
;
hsa-mir-6130
;
hsa-mir-6129
;
hsa-mir-6127
;
hsa-mir-4510
;
hsa-mir-4419a
;
hsa-mir-6727-3p
;
hsa-mir-4722-3p
;
hsa-mir-6752-3p
;
hsa-mir-6794-5p
;
hsa-mir-4716-3p
;
hsa-mir-4756-5p
;
hsa-mir-4739
;
hsa-mir-1321
;
hsa-mir-4779
;
hsa-mir-6856-5p
;
hsa-mir-6758-5p
;
hsa-mir-5006-3p
;
hsa-mir-4755-5p
;
hsa-mir-3692-3p
;
hsa-mir-29b-2-5p
;
hsa-mir-211-5p
;
hsa-mir-204-5p
;
hsa-mir-623
;
hsa-mir-642b-5p
;
hsa-mir-6070
;
hsa-mir-671-3p
;
hsa-mir-5088-3p
;
hsa-mir-4453
;
hsa-mir-4538
;
hsa-mir-3157-5p
;
hsa-mir-330-5p
;
hsa-mir-326
;
hsa-mir-4691-3p
;
hsa-mir-1306-5p
;
hsa-mir-6873-3p
;
hsa-mir-6817-3p
;
hsa-mir-7110-3p
;
hsa-mir-520f-5p
;
hsa-mir-6769b-3p
;
hsa-mir-4723-3p
;
hsa-mir-3183
;
hsa-mir-6800-3p
;
hsa-mir-6853-3p
;
hsa-mir-1206
;
hsa-mir-567
Nearest miRNA
hsa-mir-378d-1/Upstream/66890; hsa-mir-12113/Downstream/82614;
Nearest TSS
ENST00000502981/Upstream/184876;
ENST00000511199/Downstream/4484;
Nearest CpG islands
None/Target,
chr4-CpG: 46/Upstream/183674
,
chr4-CpG: 45/Downstream/104401
Upstream sequence
CAAGCAGATGTGTTTGCCCAGTTCCAGAACTGGGGCTGTGACGGGGGGGACAGATCGGACCTTCTGCCAAGGGTCTGATTCCGGTGGAAGGGAACACCGC
Downstream sequence
ATGAAGCCACATGCCACGTTCCCAGCAGGCGCTCAACAGACATTCATCACTTCAGCTTCCCCTCTGAAAGCCGAGACCACATCCTGATGCATGTTTAAAT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Sample Information
×
Sample name
HAM/TSP#3
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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