Basic Information
VIS ID
TVIS44022334
Fusion event
HTLV-1-LOC105377294 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
77868075/76946922 (Hg38)
End
77868075/76946922 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105377294
Nearest miRNA
hsa-mir-12113/Upstream/371296; hsa-mir-1243/Downstream/5806415;
Nearest TSS
ENST00000502981/Upstream/48775; ENST00000504637/Downstream/2781;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/48475, chr4-CpG: 213/Downstream/1365
Nearby gene
SEPTIN11(+2792) ;
Upstream sequence
ctgcaaaggtatgtgcaaaatgaagggaaaccaTAGGGGTTTACTCTGGGTCACCCTAGGGAGGGATACTGgctgcttcctttggttgagggaggcaacc
Downstream sequence
agcctgcaatggtgccatagtaagggagccaggggggaataaataaccatactccttcctctttgttccatcgctgttgcttcctagtgccttcactcaa
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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