VISDB Viral Integration Site DataBase

VIS ID

TVIS44022361

Fusion event

HTLV-1-EFNA5 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr5

Cytoband

q21.3

Reference genome

Start

End

106714712/107379011 (Hg38)

Orient

-

Location type

UTR3

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-92a-3p ; hsa-mir-6794-3p ; hsa-mir-6787-3p ; hsa-mir-4310 ; hsa-mir-7157-5p ; hsa-mir-4639-3p ; hsa-mir-3680-5p ; hsa-mir-4798-3p ; hsa-mir-8054 ; hsa-mir-548l ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-3692-3p ; hsa-mir-6836-3p ; hsa-mir-496 ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-6778-3p ; hsa-mir-6747-3p ; hsa-mir-1179 ; hsa-mir-1305 ; hsa-mir-576-5p ; hsa-mir-4263 ; hsa-mir-4799-5p ; hsa-mir-6883-3p ; hsa-mir-6715b-3p ; hsa-mir-454-5p ; hsa-mir-6715a-3p ; hsa-mir-3938 ; hsa-mir-501-5p ; hsa-mir-500b-5p ; hsa-mir-362-5p ; hsa-mir-10a-3p

Nearest miRNA

hsa-mir-10397/Upstream/6562446; hsa-mir-103a-1/Downstream/3134818;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/4119162, chr5-CpG: 253/Downstream/290418

Nearest cancer related gene

EFNA5(TSG, No orient, 0)

Upstream sequence

GGTTCTATTGATCCATTTTAGAAGGTATCTTTCTCCCCCTACCCAAATCCCACTGGACCAACAAGCCTGTAACTATTAATTAAAAAAAAAAAAGTATTTC

Downstream sequence

TGCATATGACTGAGAGTACTGCATATATAAATAGCTAAAGGAAAAAGGAATTGAATGCCGTGAACTTTTGTTTTGGTGAAATGGTGGCTGCCTTCTGTGA