Basic Information
VIS ID
TVIS44022373
Fusion event
HTLV-1-LINC01170 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
123621393/124285700 (Hg38)
End
123621393/124285700 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
LINC01170
Nearest miRNA
hsa-mir-10397/Upstream/5130984; hsa-mir-103a-1/Downstream/4811988;
Nearest TSS
ENST00000502646/Upstream/697275; ENST00000510004/Downstream/109339;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/649386, chr5-CpG: 48/Downstream/366005
Upstream sequence
AAAACCACGTGATTGCAAACACATCTGTCACTGACTGTCTAAGCTGCAGTCAACAACCTGATAAAGCACTGCCTCCAACACACAGAGAAAATGAGACTCA
Downstream sequence
AGGGAGTTCTCACTTTGGAGAAATCCCTTGCTGCTTTCTTATAAAGCCAGGAGCGCAGTGAAGCAAGATGCTTGGCTCACTATTCTCCAACACAAGCTTC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate