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TVIS44022379
Basic Information
VIS ID
TVIS44022379
Fusion event
HTLV-1-GRAMD2B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
125753237/126417545 (Hg38)
End
125753237/126417545 (Hg38)
Orient
+
Location type
Intronic
Target gene
GRAMD2B
miRNAs that regulate target gene
hsa-mir-124-3p
;
hsa-mir-15a-5p
;
hsa-mir-16-5p
;
hsa-mir-32-5p
;
hsa-mir-92a-3p
;
hsa-mir-15b-5p
;
hsa-mir-141-5p
;
hsa-mir-195-5p
;
hsa-mir-424-5p
;
hsa-mir-497-5p
;
hsa-mir-545-3p
;
hsa-mir-92b-3p
;
hsa-mir-1468-3p
;
hsa-mir-670-3p
;
hsa-mir-548e-5p
;
hsa-mir-548f-5p
;
hsa-mir-548g-5p
;
hsa-mir-548p
;
hsa-mir-548x-5p
;
hsa-mir-548aj-5p
;
hsa-mir-4742-5p
;
hsa-mir-6838-5p
;
hsa-mir-8063
;
hsa-mir-3145-3p
;
hsa-mir-3200-3p
;
hsa-mir-33a-3p
;
hsa-mir-409-3p
;
hsa-mir-10a-3p
Nearest miRNA
hsa-mir-10397/Upstream/7262829; hsa-mir-103a-1/Downstream/2680143;
Nearest TSS
ENST00000502646/Upstream/46232;
ENST00000505720/Downstream/5601;
Nearest CpG islands
None/Target,
chr5-CpG: 87/Upstream/1765490
,
chr5-CpG: 30/Downstream/5810
Upstream sequence
tcccagctgaagcaccagacctgggaatgaaaattccatcttgcacatccagcttagctgagtcttcaaatgacttcaaacccggcctttatctgagtgc
Downstream sequence
aaatgcatgagtgatcacaagtgacaaccattcagctgagcccagtcaatccacagaaccatgagaggtaataataaattattgttttaagccaccaggt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Sample Information
×
Sample name
HAM/TSP#3
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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