VISDB Viral Integration Site DataBase

VIS ID

TVIS44022425

Fusion event

HTLV-1-ATP6V0E1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr5

Cytoband

q35.1

Reference genome

Start

End

172458408/173031405 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-132-3p ; hsa-mir-218-5p ; hsa-mir-181a-5p ; hsa-mir-15b-5p ; hsa-mir-16-5p ; hsa-mir-17-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-7977 ; hsa-mir-3178 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-4786-5p ; hsa-mir-342-3p ; hsa-mir-5739 ; hsa-mir-5091 ; hsa-mir-383-3p ; hsa-mir-1228-3p ; hsa-mir-1247-3p ; hsa-mir-1267 ; hsa-mir-1273e ; hsa-mir-1273g-3p ; hsa-mir-1827 ; hsa-mir-1910-3p ; hsa-mir-219b-3p ; hsa-mir-2467-3p ; hsa-mir-302f ; hsa-mir-3140-5p ; hsa-mir-3160-3p ; hsa-mir-3612 ; hsa-mir-367-5p ; hsa-mir-377-5p ; hsa-mir-4257 ; hsa-mir-4466 ; hsa-mir-4487 ; hsa-mir-455-3p ; hsa-mir-4652-3p ; hsa-mir-4722-5p ; hsa-mir-4766-5p ; hsa-mir-4768-3p ; hsa-mir-4778-5p ; hsa-mir-4793-5p ; hsa-mir-5196-3p ; hsa-mir-548l ; hsa-mir-558 ; hsa-mir-6086 ; hsa-mir-6499-3p ; hsa-mir-650 ; hsa-mir-6511a-5p ; hsa-mir-6516-5p ; hsa-mir-675-5p ; hsa-mir-106a-5p ; hsa-mir-1236-3p ; hsa-mir-1273f ; hsa-mir-130a-3p ; hsa-mir-130b-3p ; hsa-mir-143-3p ; hsa-mir-1468-3p ; hsa-mir-20a-3p ; hsa-mir-2276-5p ; hsa-mir-301a-3p ; hsa-mir-301b-3p ; hsa-mir-33a-5p ; hsa-mir-33b-5p ; hsa-mir-3613-3p ; hsa-mir-3666 ; hsa-mir-3674 ; hsa-mir-4295 ; hsa-mir-454-3p ; hsa-mir-4708-5p ; hsa-mir-4770 ; hsa-mir-519a-3p ; hsa-mir-519b-3p ; hsa-mir-519c-3p ; hsa-mir-520g-3p ; hsa-mir-520h ; hsa-mir-526b-3p ; hsa-mir-548aj-5p ; hsa-mir-548an ; hsa-mir-548aw ; hsa-mir-548f-5p ; hsa-mir-548g-5p ; hsa-mir-548x-5p ; hsa-mir-570-3p ; hsa-mir-6088 ; hsa-mir-642a-5p ; hsa-mir-651-3p ; hsa-mir-6822-3p ; hsa-mir-6892-3p ; hsa-mir-760 ; hsa-mir-8057

Nearest miRNA

hsa-mir-10397/Upstream/116247; hsa-mir-12118/Downstream/272325;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/47247, chr5-CpG: 105/Downstream/24707

Upstream sequence

actcctgacctcaagtgatccacccaccatggcctcccaaagtactgggattacaggcatgagccaccgcatccgaccCTTTGTCAGTTTTATCTGATGG

Downstream sequence

TAACCTTATGACTCTTTTTTTTTTTTTTTTTGAGACGTGCAAAATGAGAACATGGACCCTTTGATTAAGTTCTTCAGCCCCACCCCCAGTCAGCTATTTC