Basic Information
VIS ID
TVIS44022427
Fusion event
HTLV-1-LOC105377732 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q35.2
Reference genome
GRCh37/hg19
Start
172900576/173473573 (Hg38)
End
172900576/173473573 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA5G
Target gene
LOC105377732
Nearest miRNA
hsa-mir-10397/Upstream/126037; hsa-mir-1229/Downstream/1278161;
Nearest TSS
ENST00000502646/Upstream/3891; ENST00000519821/Downstream/88905;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/143478, chr5-CpG: 56/Downstream/142547
Nearby gene
LOC285593(+106061) ;
Upstream sequence
ttcctggcaggcagaaggcacttagtaaacatttgctgaacgaTCgagtgaataaatgaataaatgaatgaatgaCATCCACAGGCATTTTTGTGTGTGT
Downstream sequence
ATGATGAGACATATGAGGTTTCCAGGACACCAGAAACTCCTACAGTCATCCATTCTAGTATGTCACGACGTTGTCACTGGAAGGCCCTTTTAAAAATCAC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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