Basic Information
VIS ID
TVIS44022445
Fusion event
HTLV-1-chr5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
31395733/31395626 (Hg38)
End
31395733/31395626 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA5A
Nearest miRNA
hsa-mir-10397/Upstream/14239634; hsa-mir-103a-1/Downstream/540476;
Nearest TSS
ENST00000502646/Upstream/79376; ENST00000515409/Downstream/11330;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/201314, chr5-CpG: 42/Downstream/136377
Nearby gene
DROSHA(-4869) ;
Upstream sequence
aagactgagaaggctgcgccagtgtccagcagatggttaacctcctggccctcaatggtcaagcatacccggggctctgtgagggtgatggcatgggctg
Downstream sequence
gcgcttgcccccggcaccctcagtcctgctgctgtatcatctggttagtggcttctgactcagaggaccttcgtcccctggggcagtgggcctttcagtg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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