Basic Information
VIS ID
TVIS44022447
Fusion event
HTLV-1-chr5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
34466813/34466708 (Hg38)
End
34466813/34466708 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA5A
Nearest miRNA
hsa-mir-10397/Upstream/2072233; hsa-mir-103a-1/Downstream/1681184;
Nearest TSS
ENST00000502646/Upstream/308587; ENST00000510386/Downstream/185180;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/458480, chr5-CpG: 131/Downstream/189310
Nearby gene
RAI14(+189620) ;
Upstream sequence
tctgttaccatcctccattttcctgaccttttttgtacaacaaacatgggcgagttccatggagacaaggagggctcaatagtgtttgcttgtagtaaat
Downstream sequence
cattaacaatttcagttaaagcctccaacttgtgtttggaaagtggccactgctctacccaaacaggtgactcacacatccattgtgcaggggcagagga
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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