Basic Information
VIS ID
TVIS44022456
Fusion event
HTLV-1-chr5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p15.33
Reference genome
GRCh37/hg19
Start
4114760/4114647 (Hg38)
End
4114760/4114647 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-4277/Upstream/2405779; hsa-mir-10397/Downstream/2713206;
Nearest TSS
ENST00000502646/Upstream/72883; ENST00000503415/Downstream/21035;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/152249, chr5-CpG: 39/Downstream/751557
Nearby gene
IRX1(+513243) ;
Nearest cancer related gene
IRX1(TSG, +513243) ;
Upstream sequence
TTCACGAGACCGTAACCTGCAGGCCCAAGCCACAAGTTTAGTAAGGCTGTAGTTTACAGCTCTCGCAGACATGATGTCACCAGCCTTGTGTGAGTGCATG
Downstream sequence
GTGGCACAGACAGAGGTCACACACTGTCACACACTGATACACATGTACAGGATGACAGAATCACAGTGTCTcacttacacatgcaggcacacacgtgcac
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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