VISDB Viral Integration Site DataBase

VIS ID

TVIS44022469

Fusion event

HTLV-1-ITGA2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr5

Cytoband

q11.2

Reference genome

Start

End

52300274/53004444 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-16-5p ; hsa-mir-30a-5p ; hsa-mir-335-5p ; hsa-mir-103a-3p ; hsa-mir-15a-5p ; hsa-mir-107 ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-1255a ; hsa-mir-1255b-5p ; hsa-mir-6838-5p ; hsa-mir-18a-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-363-5p ; hsa-mir-18b-5p ; hsa-mir-1293 ; hsa-mir-548n ; hsa-mir-3919 ; hsa-mir-4483 ; hsa-mir-4506 ; hsa-mir-4694-5p ; hsa-mir-4735-3p ; hsa-mir-5680 ; hsa-mir-548aw ; hsa-mir-6745 ; hsa-mir-6756-5p ; hsa-mir-6766-5p ; hsa-mir-6885-3p ; hsa-mir-1273e ; hsa-mir-580-3p ; hsa-mir-636 ; hsa-mir-4804-3p ; hsa-mir-4720-3p ; hsa-mir-539-5p ; hsa-mir-3121-5p ; hsa-mir-520f-3p ; hsa-mir-302c-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-520a-3p ; hsa-mir-372-3p ; hsa-mir-302d-3p ; hsa-mir-302a-3p ; hsa-mir-302b-3p ; hsa-mir-373-3p ; hsa-mir-520b ; hsa-mir-520c-3p ; hsa-mir-520d-3p ; hsa-mir-520e ; hsa-mir-302e ; hsa-mir-514b-5p ; hsa-mir-513c-5p ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-873-5p ; hsa-mir-5004-3p ; hsa-mir-432-3p ; hsa-mir-196a-3p ; hsa-mir-6744-5p ; hsa-mir-4468 ; hsa-mir-891b ; hsa-mir-649 ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-1247-3p ; hsa-mir-1297 ; hsa-mir-1976 ; hsa-mir-26a-5p ; hsa-mir-26b-5p ; hsa-mir-3653-5p ; hsa-mir-4279 ; hsa-mir-4465 ; hsa-mir-4532 ; hsa-mir-4722-3p ; hsa-mir-4740-3p ; hsa-mir-5001-3p ; hsa-mir-6513-3p ; hsa-mir-6727-3p ; hsa-mir-6747-3p ; hsa-mir-6778-3p ; hsa-mir-6787-3p ; hsa-mir-6791-3p ; hsa-mir-6829-3p ; hsa-mir-6836-3p ; hsa-mir-8062

Nearest miRNA

hsa-mir-10397/Upstream/14446883; hsa-mir-103a-1/Downstream/947060;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/14785, chr5-CpG: 44/Downstream/104995

Upstream sequence

ttgggtcattgggaagatcgaaggggattataagtgaaaaagtatttttcatattgtaaaAGCATATGGAATATTATTTAAAAAAAAATCAGTACACTTG

Downstream sequence

GTATGCATCCATTTTTATCATCATTCATTTATTTAAGGGACCTTCTTAAGGGACTTTTATGGAGTGCCTATTGTATACCCACAGAGTGTCAGGCCTGGGG