Basic Information
VIS ID
TVIS44022477
Fusion event
HTLV-1-chr5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p15.32
Reference genome
GRCh37/hg19
Start
5662903/5662790 (Hg38)
End
5662903/5662790 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-4277/Upstream/3953922; hsa-mir-10397/Downstream/1165063;
Nearest TSS
ENST00000502646/Upstream/240048; ENST00000568962/Downstream/359493;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/167526, chr5-CpG: 37/Downstream/224159
Nearby gene
ICE1(No orient, 172556)
Upstream sequence
ATTCCTACTGACCTGTCCTGTGGGCAGAATTACCTTTCAGCACCCACCCACTGCTGTCAAACCACCACAGCCCTGCTCCTTTACGGCCCTACGTAAACCA
Downstream sequence
AGTGGTTATTTCACTTCTGATGTCCTTCTATGATGATGACCGTGCTATTACACTGTAAACTCCAGGAGGGGAGAAACTATGATTTCCAGTTCTTTAGAAT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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