VISDB Viral Integration Site DataBase

VIS ID

TVIS44022516

Fusion event

HTLV-1-CD164 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr6

Cytoband

q21

Reference genome

Start

End

109701944/109380741 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-192-5p ; hsa-mir-132-3p ; hsa-mir-215-5p ; hsa-mir-93-5p ; hsa-mir-130b-3p ; hsa-let-7c-3p ; hsa-mir-495-3p ; hsa-mir-5688 ; hsa-mir-513a-3p ; hsa-mir-513c-3p ; hsa-mir-3606-3p ; hsa-mir-181b-3p ; hsa-mir-181b-2-3p ; hsa-mir-4420 ; hsa-mir-548av-3p ; hsa-mir-548k ; hsa-mir-548l ; hsa-mir-548av-5p ; hsa-mir-8054 ; hsa-mir-570-3p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-1231 ; hsa-mir-632 ; hsa-mir-4288 ; hsa-mir-6755-3p ; hsa-mir-346 ; hsa-mir-4480 ; hsa-mir-4793-3p ; hsa-mir-3130-3p ; hsa-mir-335-5p ; hsa-mir-548g-3p ; hsa-mir-4670-3p ; hsa-mir-586 ; hsa-mir-4718 ; hsa-mir-520f-5p ; hsa-mir-4509 ; hsa-mir-4744 ; hsa-mir-4428 ; hsa-mir-1283 ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-3157-5p ; hsa-mir-4691-3p ; hsa-mir-6513-3p ; hsa-mir-512-5p ; hsa-mir-551b-5p ; hsa-mir-186-5p ; hsa-mir-3133 ; hsa-mir-4263 ; hsa-mir-376b-3p ; hsa-mir-376a-3p ; hsa-mir-653-3p ; hsa-mir-4724-3p ; hsa-mir-6740-3p ; hsa-mir-27b-5p ; hsa-mir-1208 ; hsa-mir-6760-3p ; hsa-mir-6782-3p

Nearest miRNA

hsa-mir-10398/Upstream/2596521; hsa-mir-1202/Downstream/9688306;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/89714, chr6-CpG: 106/Downstream/954

Upstream sequence

GTAGCAAAGTGAAATGTCTGAAATGTTCTTTACAATGAACTAAACTTGCTACCTTTCAGACCACACTACATCCACTTATGATTTCCAGAAAATACATACC

Downstream sequence

TCCTTTGCACGCACTTCAATTACACAAAGACAAATTAATTTGATACTTCCAACCTTCTCTTACACACACACTACAATTCTGAAAGGAAACTGTCAAATTA