Basic Information
VIS ID
TVIS44022521
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p24.2
Reference genome
GRCh37/hg19
Start
11429161/11428928 (Hg38)
End
11429161/11428928 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105374928 ; LOC105374929
Nearest miRNA
hsa-mir-3691/Upstream/989134; hsa-mir-10398/Downstream/4712628;
Nearest TSS
ENST00000381078/Upstream/11578; ENST00000423149/Downstream/58298;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/334494, chr6-CpG: 182/Downstream/108376
Nearby gene
NEDD9(-46580) ;
Upstream sequence
AACATTTAGTCCTTGTTTTAAATATCAAGTGATTGTTTTCTGCATCAAATTTAGAATTCCGGTTTTGCCAAACACATCTCAGAGAAACAGGCTGGCCCCT
Downstream sequence
GAGCCAGACAGCAGTTGTAAACATCTCTTCTTCCTGTTTAGAGACAGTACTGAATTCCAGAGCTGGACCTGTGAAATACCAGCGCTCCTCTCCCTCTAGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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