Basic Information
VIS ID
TVIS44022528
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
131054347/130733202 (Hg38)
End
131054347/130733202 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10398/Upstream/4248489; hsa-mir-1202/Downstream/1058970;
Nearest TSS
ENST00000381078/Upstream/35890; ENST00000541421/Downstream/94204;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/366611, chr6-CpG: 144/Downstream/329089
Nearby gene
SMLR1(No orient, 94198)
Upstream sequence
ACATGAATTCCTTtcattttaagttataataaaaacttcatattttatgcccccaatttctcggaagccttctgaagccatagtttttgagcctatggac
Downstream sequence
cgtggcatgcttttAAAGCCAATAAATGACCACCCCTTGCCCTCACCAAATTTCCTTACTAATTTCACTCTCTTTTTTACCTTGTTAAATACTGTAATTC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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