Basic Information
VIS ID
TVIS44022533
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p23
Reference genome
GRCh37/hg19
Start
14306074/14305843 (Hg38)
End
14306074/14305843 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA6A
Nearest miRNA
hsa-mir-3691/Upstream/3866049; hsa-mir-10398/Downstream/1835713;
Nearest TSS
ENST00000381078/Upstream/20389; ENST00000434947/Downstream/87445;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/94330, chr6-CpG: 113/Downstream/938803
Nearby gene
LINC01108(No orient, 20389)
Upstream sequence
TGTACCCTGAAAGCCAAGCCTCAAGTATTCACGGCTTGCTATCTCCAGGGTAATTAAAGGGGAGAGAGTAAATCACACACTGAAAAACAGCCCTGAGTGC
Downstream sequence
TTAAGTACATGTCAGTCACCGAGACTGGCATCTACTCAGAGTGGAGGAGACCTGGGGTTTGCATTACACACAACACCCCATGAGATCATTAGGGCTACTT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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