Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene166368022166319728166342591166305300166308448166317565166319643166275462166277077166298349166299945166307529166308974166301971166303222166314989166316214166286400166287591166306193166307125166300134166300941166293888166294688166294722166295463166292571166293311166297666166298083166275543166275942166307153166307502166303702166304015166276053166276182166321742
Basic Information
VIS ID
TVIS44022543
Fusion event
HTLV-1-SFT2D1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q27
Reference genome
GRCh37/hg19
Start
166735230/166321742 (Hg38)
End
166735230/166321742 (Hg38)
Orient
+
Location type
Intronic
Target gene
SFT2D1
miRNAs that regulate target gene
hsa-mir-425-5p ; hsa-mir-15b-5p ; hsa-let-7g-5p
Nearest miRNA
hsa-mir-10398/Upstream/7556989; hsa-mir-1913/Downstream/187612;
Nearest TSS
ENST00000381078/Upstream/13294; ENST00000568025/Downstream/2946;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/12955, chr6-CpG: 73/Downstream/20582
Upstream sequence
TTTTGCTGTTTTTAAATATATAACATATCTTTGAATTTCACAAACAGGCAAAGCTGTGCCTCACCAGAATCTTTTTCTAAATCTATCAGATTTAAAATTG
Downstream sequence
GAACTAGTTTTGTTTTCTCCTCCACGGCTAAATACATTTCTCTGGAAAAATATTTTAAAATGCCGGTTACCTCTTGACATACAATTAAAATGTTTTTGCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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