VISDB Viral Integration Site DataBase

VIS ID

TVIS44022544

Fusion event

HTLV-1-CCR6 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr6

Cytoband

q27

Reference genome

Start

End

167548965/167135477 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-518a-3p ; hsa-mir-150-5p ; hsa-mir-127-5p ; hsa-mir-7843-3p ; hsa-mir-4749-3p ; hsa-mir-6806-3p ; hsa-mir-3928-5p ; hsa-mir-4635 ; hsa-mir-4539 ; hsa-mir-106a-3p ; hsa-mir-6879-3p ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-564 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-500b-3p ; hsa-mir-183-5p ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-301a-3p ; hsa-mir-301b-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-5197-5p ; hsa-mir-640 ; hsa-mir-5579-3p ; hsa-mir-1245a ; hsa-mir-8079 ; hsa-mir-129-5p ; hsa-mir-8055 ; hsa-mir-4309 ; hsa-mir-3198 ; hsa-mir-4294 ; hsa-mir-1289 ; hsa-mir-8082 ; hsa-mir-4534 ; hsa-mir-1273f ; hsa-mir-4708-5p ; hsa-mir-6088 ; hsa-mir-4770 ; hsa-mir-143-3p ; hsa-mir-3124-3p ; hsa-mir-6514-5p ; hsa-mir-150-3p ; hsa-mir-4315 ; hsa-mir-4790-5p

Nearest miRNA

hsa-mir-10398/Upstream/137565; hsa-mir-4644/Downstream/3195284;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/135543, chr6-CpG: 17/Downstream/38389

Upstream sequence

CTACTGGAAAGGTCTGCGGCTGTGGAGAAGCAGGTGCATTCCTCTCCAGCGCCTTCCCAGGCTGGAGCAGCTTGTTCAGTGTGTCTTGAGAACAGCACTC

Downstream sequence

ATAGTCAAACTTTAAATTCTACTGGAGATTCTCACATGCCCACAGGGGTGATCATCACTGACATATATTGTGAACGATTTAAAGCCCGGGACTATGAATT