Basic Information
VIS ID
TVIS44022552
Fusion event
HTLV-1-CASC15 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
21872177/21871946 (Hg38)
End
21872177/21871946 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
CASC15
Nearest miRNA
hsa-mir-3691/Upstream/3300066; hsa-mir-10398/Downstream/5275680;
Nearest TSS
ENST00000381078/Upstream/203127; ENST00000605917/Downstream/26774;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/205315, chr6-CpG: 100/Downstream/697409
Upstream sequence
TTTTAGAGAAGAAATGTTCTGTTTTCTAGAAGCATTTTCTAACTTCTCAAGGGGCCAACCGAAGTTTACTTTCGTTGTTCTTCTGTACGTGTGCCTGGTT
Downstream sequence
TCCTAAAGCCCTTTGCTTGGGAACAGCTCACTCAGTGAGGCTGCCTGGGGTGTTGCAGCCTCAGGTGTTGGTGGTGTAGGGTTTTCTGTGCTTGCCCTTC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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