Basic Information
VIS ID
TVIS44022556
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p22.2
Reference genome
GRCh37/hg19
Start
26205410/26205182 (Hg38)
End
26205410/26205182 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA6C
Nearest miRNA
hsa-mir-3691/Upstream/7633302; hsa-mir-10398/Downstream/942444;
Nearest TSS
ENST00000381078/Upstream/630; ENST00000303910/Downstream/11510;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/197, chr6-CpG: 32/Downstream/11801
Nearby gene
HIST1H4E(+161) ;
Upstream sequence
TTGTTCCTGTCAACAGGTACGTATATTTTTCAGCCGTTTTTTTTTTTTCGTTCCAAATTACATTTGGGGTTTCGGCATACGATTTTTTAGGCTACGATCC
Downstream sequence
TTTTATGTTTATTGTAGTAGGGCCTTAGATTGCACTGAAAAGGCTAGGGTAATAGTGTCTGTTTACCTTACCACTTTTATTTTGAGTACCTAAAAATGCA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate