VISDB Viral Integration Site DataBase

VIS ID

TVIS44022574

Fusion event

HTLV-1-KIF6 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr6

Cytoband

p21.2

Reference genome

Start

End

39588797/39621021 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-339-5p ; hsa-mir-125a-5p ; hsa-mir-6515-5p ; hsa-mir-6807-5p ; hsa-mir-4443 ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-8077 ; hsa-mir-496 ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-1233-3p ; hsa-mir-1225-3p ; hsa-mir-135b-5p ; hsa-mir-135a-5p ; hsa-mir-889-5p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-4776-3p ; hsa-mir-192-3p ; hsa-mir-661 ; hsa-mir-3116 ; hsa-mir-1254 ; hsa-mir-5189-3p ; hsa-mir-4772-5p ; hsa-mir-4748 ; hsa-mir-4464 ; hsa-mir-3591-3p ; hsa-mir-21-3p ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-185-5p ; hsa-mir-6501-3p ; hsa-mir-6715a-3p ; hsa-mir-6760-5p ; hsa-mir-4701-5p ; hsa-mir-5089-5p ; hsa-mir-5589-5p ; hsa-mir-6506-5p ; hsa-mir-4731-5p ; hsa-mir-619-5p ; hsa-mir-512-3p ; hsa-mir-4433b-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-6801-5p ; hsa-mir-6780b-5p ; hsa-mir-4725-3p ; hsa-mir-4271 ; hsa-mir-671-5p ; hsa-mir-4313 ; hsa-mir-345-3p ; hsa-mir-6798-5p ; hsa-mir-6718-5p ; hsa-mir-203b-5p ; hsa-mir-6783-5p ; hsa-mir-3943 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-7157-5p ; hsa-mir-4310 ; hsa-mir-186-5p ; hsa-mir-3133

Nearest miRNA

hsa-mir-1236/Upstream/546640; hsa-mir-10398/Downstream/1977702;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/306582, chr6-CpG: 34/Downstream/103946

Upstream sequence

ttgcacccagctaatttttatatttttagtagagacagggttttgccatgttagccaggctggtcttgaactcctgaccttaggtgatttgcccaccctg

Downstream sequence

gccgctcaaagtgctgggattacaggtgtgagccaccgcacccagccTACaacatttttttaatagttacacaatattttagggttaggatgtattaatg