Basic Information
VIS ID
TVIS44022580
Fusion event
HTLV-1-LOC107986599 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
44123746/44156009 (Hg38)
End
44123746/44156009 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA6H
Target gene
LOC107986599
Nearest miRNA
hsa-mir-10398/Upstream/721389; hsa-mir-10524/Downstream/98197;
Nearest TSS
ENST00000381078/Upstream/16297; ENST00000526118/Downstream/2802;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/3177, chr6-CpG: 24/Downstream/63440
Nearby gene
TMEM63B(+490) ;
Upstream sequence
TGATCTCCTCAAtgagaagccccctcccaccctccagtcaaatcttacccattctccaagacccagctcaaattcaccttctcgccaggcgcggtggctc
Downstream sequence
acgcctgtaatcccagtactttgggaggccaaggtgggtggatcacttgagttcaggagttcgagaccagcctggccaacatgatgaaaccccatctcta
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate