Basic Information
VIS ID
TVIS44022581
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p25.3
Reference genome
GRCh37/hg19
Start
441592/441592 (Hg38)
End
441592/441592 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10398/Downstream/948722;
Nearest TSS
ENST00000381078/Upstream/48313; ENST00000430842/Downstream/82579;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/16765, chr6-CpG: 258/Downstream/77487
Nearby gene
IRF4(+30149) ;
Nearest cancer related gene
IRF4(TSG, +30149) ;
Upstream sequence
AGCCCTCCATTCCCACACCAAGACAAGTGCCCCAGGGGCCTTTCACAGGTGAAGGGTGGCCCATCTTGCCAGCTCACCCAGGACCCACAGAGGGGTCTCG
Downstream sequence
GCACTTATTCTTCTGTCACCTCCCAAATCTCTCCTGCACCTCCAGCCTCAAGGAGAGTGGCCTCTTCAGTTCTCTCCACCATGCTTCCGGTGGCAGGACT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate