Basic Information
VIS ID
TVIS44022599
Fusion event
HTLV-1-LOC105374898 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p25.1
Reference genome
GRCh37/hg19
Start
5969612/5969379 (Hg38)
End
5969612/5969379 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA6B
Target gene
LOC105374898
Nearest miRNA
hsa-mir-3691/Upstream/821057; hsa-mir-10398/Downstream/199925;
Nearest TSS
ENST00000381078/Upstream/117873; ENST00000230568/Downstream/33584;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/117771, chr6-CpG: 20/Downstream/25297
Nearby gene
NRN1(-28621) ;
Upstream sequence
GGTTCGGTGCTGTATGTAGGtcccagttaatcttcacaatgaccctgtgaggttgttgttttcctctccttttctgtaaatgaggagcctgcaggcactg
Downstream sequence
agggagagatgatgaactcgaaatcacccagcttgcaaatgatagagatgggaccaaccctggtgctgtcgtgtcccacaccccattctctGGCTTGACT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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