VISDB Viral Integration Site DataBase

VIS ID

TVIS44022635

Fusion event

HTLV-1-BACH2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr6

Cytoband

q15

Reference genome

Start

End

90736306/90026587 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-29c-3p ; hsa-mir-615-3p ; hsa-mir-8064 ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-6083 ; hsa-mir-5011-5p ; hsa-mir-656-3p ; hsa-mir-410-3p ; hsa-mir-3942-3p ; hsa-mir-1324 ; hsa-mir-8485 ; hsa-mir-6797-3p ; hsa-mir-6076 ; hsa-mir-6807-3p ; hsa-mir-217 ; hsa-mir-509-5p ; hsa-mir-509-3-5p ; hsa-mir-4418 ; hsa-mir-6749-3p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-2355-5p ; hsa-mir-15b-3p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-6832-3p ; hsa-mir-620 ; hsa-mir-1270 ; hsa-mir-4531 ; hsa-mir-5703 ; hsa-mir-4516 ; hsa-mir-4434 ; hsa-mir-5695 ; hsa-mir-3145-5p ; hsa-let-7g-3p ; hsa-let-7a-2-3p ; hsa-mir-374b-5p ; hsa-mir-374a-5p ; hsa-mir-4791 ; hsa-mir-3201 ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-369-3p ; hsa-mir-5583-3p ; hsa-mir-4517 ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-4726-3p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-6840-3p ; hsa-mir-142-5p

Nearest miRNA

hsa-mir-10398/Upstream/11487278; hsa-mir-1202/Downstream/286155;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/138653, chr6-CpG: 227/Downstream/268489

Upstream sequence

GCTTATAGATGCTAATATGTATAACCTGCCAAAGTTAGATTCATCTGACCAGGGATTATGATGTTAAGAGACTGGATTGTCAAACCTAACTCCTTCTTGG

Downstream sequence

AATGGGGGTGGGGGTTACCTCCAGACACACTTTTGTCTGCCTATACATAAAGAATATCTATAGTTTCACAGCTGTTCATCCGCCTGATCTCTACTGTTGC