Basic Information
VIS ID
TVIS44022643
Fusion event
HTLV-1-chr7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
101340253/101696973 (Hg38)
End
101340253/101696973 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA7F
Nearest miRNA
hsa-mir-10525/Upstream/537418; hsa-mir-10399/Downstream/596130;
Nearest TSS
ENST00000635602/Upstream/67677; ENST00000607092/Downstream/118931;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/8349, chr7-CpG: 53/Downstream/46301
Nearby gene
MYL10(-67677) ;
Upstream sequence
gtggtggctcatgcctgtaatcctaatgctttgggaggcttaggcaggagaactgcttgaggccatgtgtttgagatcagcctgggcaacatagtgggac
Downstream sequence
cccatcccaaaaaaaattttttttaaagagggtgggtgcatggccgggagtggtggctcatgcctataatccctttgggaggccaaggcgggtcgatcac
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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