Basic Information
VIS ID
TVIS44022655
Fusion event
HTLV-1-chr7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q31.31
Reference genome
GRCh37/hg19
Start
118465565/118825511 (Hg38)
End
118465565/118825511 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10525/Upstream/1805192; hsa-mir-10399/Downstream/8232577;
Nearest TSS
ENST00000635602/Upstream/585536; ENST00000421825/Downstream/1081864;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/610844, chr7-CpG: 93/Downstream/1447275
Nearby gene
ANKRD7(+582781) ;
Upstream sequence
tcattccttggtaggggccctctcccgccctgctcatgtctgactgacttcctactgtaacaCACATATGTTTTGAAAGATTATTTAGGAAGGAAAGTGG
Downstream sequence
ATATTTATCTTAAAAAATGTGTGTTCTATTTCAAAATGGTTGACCAACCAAACACAGACATTTGCCTTCTCCCCTTCCCAAATGCAATTAAAAAGATAGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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