Basic Information
VIS ID
TVIS44022665
Fusion event
HTLV-1-chr7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q32.3
Reference genome
GRCh37/hg19
Start
131310707/131625948 (Hg38)
End
131310707/131625948 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA7H
Nearest miRNA
hsa-mir-10525/Upstream/748409; hsa-mir-10399/Downstream/1408912;
Nearest TSS
ENST00000635602/Upstream/67731; ENST00000452219/Downstream/271693;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/67701, chr7-CpG: 35/Downstream/319467
Nearby gene
PODXL(-69331) ;
Upstream sequence
aaagacacacagaagtgacttgttcctgagacatgcagtgagtcaacagctggggcgtcctggagcctgggtctccctgcccccgtgggtctctctgACA
Downstream sequence
GTGCCCTGAGTTTCTGCCTGCTGCTGGCCGTCTTGGGGCCCTGCCTCCCATCTTGCAGCTGACCCTGGCCGGAAACTCCGCCCCATTGTCTTAGGCCTCG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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