Basic Information
VIS ID
TVIS44022669
Fusion event
HTLV-1-CALD1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q33
Reference genome
GRCh37/hg19
Start
134635680/134950929 (Hg38)
End
134635680/134950929 (Hg38)
Orient
-
Location type
Intronic
Target gene
CALD1
miRNAs that regulate target gene
hsa-mir-122-5p ; hsa-mir-34a-5p ; hsa-mir-21-5p ; hsa-mir-149-5p ; hsa-mir-15a-5p
Nearest miRNA
hsa-mir-10525/Upstream/1659941; hsa-mir-10399/Downstream/256065;
Nearest TSS
ENST00000635602/Upstream/554; ENST00000473714/Downstream/9602;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/491618, chr7-CpG: 63/Downstream/35439
Upstream sequence
cctgtaataatctcagctacttgggaggcttaggcaggagaatcacttgaacccaggaggcagaggttgcagtgagctaagataatgccactgcactcta
Downstream sequence
gcctgggcaacagagcaagattccatctcaaaatttatcactcacagttttggaggctggaaagtcaaagatcaaggtgccagcagatgtggtgtctagt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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