Basic Information
VIS ID
TVIS44022671
Fusion event
HTLV-1-ATP6V0A4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q34
Reference genome
GRCh37/hg19
Start
138411294/138726549 (Hg38)
End
138411294/138726549 (Hg38)
Orient
-
Location type
Intronic
Target gene
ATP6V0A4
Nearest miRNA
hsa-mir-10525/Upstream/602728; hsa-mir-10399/Downstream/317551;
Nearest TSS
ENST00000635602/Upstream/25197; ENST00000472775/Downstream/21126;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/61429, chr7-CpG: 17/Downstream/141366
Upstream sequence
TGCCCACGGGGCATGTCACCAGGGCCACGCCACAGGCGGCCCTCTAGTGGAGAGGTTCCCAGGCCACATTCTGCAGGGACCCAGGTTGTAGGAGAGGCTA
Downstream sequence
ATAGACAGGACCCCTGTTCATATCACCTGAAGTCCGTCAGAACAAATTGTTTATGTATTAGGTCTGTAGGATTTCATGAAGGAGAGGTGGAGAAGGGGCA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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