Basic Information
VIS ID
TVIS44022681
Fusion event
HTLV-1-chr7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q36.1
Reference genome
GRCh37/hg19
Start
148234817/148537725 (Hg38)
End
148234817/148537725 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA7I
Nearest miRNA
hsa-mir-10399/Upstream/1159604; hsa-mir-153-2/Downstream/2700696;
Nearest TSS
ENST00000635602/Upstream/34267; ENST00000307003/Downstream/34452;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/197969, chr7-CpG: 200/Downstream/160613
Nearby gene
C7orf33(No orient, 52840)
Upstream sequence
AGAGTGGAAGAACCCTGATTATGTCAGTCTCTTTCATAACCCTCCACGGCCCTCTATTATCTAACCAAGATGACTCTTGGTCTGACATCAGGATTCTCTG
Downstream sequence
CGACAGCCCATCCTCCACAACCCATCCCTCTAATTACTGGGacagcacagtgattaagagtgaaccatggaggtaggactctttgactcaaaccctacct
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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