Basic Information
VIS ID
TVIS44022690
Fusion event
HTLV-1-chr7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q36.3
Reference genome
GRCh37/hg19
Start
157317976/157525282 (Hg38)
End
157317976/157525282 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA7I
Nearest miRNA
hsa-mir-10399/Upstream/6091643; hsa-mir-153-2/Downstream/49054;
Nearest TSS
ENST00000635602/Upstream/11988; ENST00000409610/Downstream/88741;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/23459, chr7-CpG: 19/Downstream/250
Nearby gene
PTPRN2(-13770) ;
Upstream sequence
ccaacaagggactaatacccagaatctacaaggaactcacccagctcaacagcaacaaaaataatctgatttaaaaatgggcaaatttcagcaggtcatg
Downstream sequence
gactaaaaaaataaaaaataagaaaaatgggcaaacgatcagagtagatgtttctcagaagaagacctaccagtggccagaaagtatatgagaaaagacc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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