Basic Information
VIS ID
TVIS44022703
Fusion event
HTLV-1-INMT-MINDY4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p14.3
Reference genome
GRCh37/hg19
Start
30823823/30784207 (Hg38)
End
30823823/30784207 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
INMT-MINDY4
Nearest miRNA
hsa-mir-1183/Upstream/494317; hsa-mir-10399/Downstream/1948774;
Nearest TSS
ENST00000635602/Upstream/4671; ENST00000409881/Downstream/19203;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/12273, chr7-CpG: 144/Downstream/267895
Upstream sequence
ACAAGCAATTAGCACAAGGATTCAGAGGTGGAGGTTCATAAGGGGCTATGAAGAAGCTCTTCCTCCGAGGCACTTACTACCTGGCTGGGAAGTGAAATAC
Downstream sequence
TTCTGGTACAATAAAAAGGCAACTAGGAAGTTGAAGCTCCTGAGTCCCACccagttacccaagccaaaaatttgggtgttcttgcctccgcctcgtccgt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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