VISDB Viral Integration Site DataBase

VIS ID

TVIS44022710

Fusion event

HTLV-1-YAE1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr7

Cytoband

p14.1

Reference genome

Start

End

39633586/39593987 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-542-3p ; hsa-mir-4650-3p ; hsa-mir-98-5p ; hsa-mir-4500 ; hsa-mir-4458 ; hsa-let-7i-5p ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-6831-5p ; hsa-mir-3927-3p ; hsa-mir-6782-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6825-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-6827-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4419a ; hsa-mir-4510 ; hsa-mir-7113-3p ; hsa-mir-6070 ; hsa-mir-671-3p ; hsa-mir-6791-5p ; hsa-mir-4292 ; hsa-mir-4308 ; hsa-mir-6873-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-6794-3p ; hsa-mir-6845-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-486-5p ; hsa-mir-4639-3p ; hsa-mir-3680-5p ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-4789-5p ; hsa-mir-3941 ; hsa-mir-1284 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-200b-5p ; hsa-mir-200a-5p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-664b-3p ; hsa-mir-579-3p ; hsa-mir-6870-3p ; hsa-mir-5696 ; hsa-mir-153-5p ; hsa-mir-1250-3p ; hsa-mir-664a-3p ; hsa-mir-586 ; hsa-mir-29c-3p ; hsa-mir-29b-3p ; hsa-mir-29a-3p ; hsa-mir-1270 ; hsa-mir-129-5p ; hsa-mir-139-3p ; hsa-mir-431-5p ; hsa-mir-4524a-3p ; hsa-mir-4531 ; hsa-mir-5007-5p ; hsa-mir-5691 ; hsa-mir-620 ; hsa-mir-6805-3p ; hsa-mir-7850-5p

Nearest miRNA

hsa-mir-1183/Upstream/2674555; hsa-mir-10399/Downstream/3556908;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/27210, chr7-CpG: 27/Downstream/15667

Upstream sequence

atgaagcattctgtggttggtctctagtgattgtcttttccttagagtgttggttgatcacattttcctgtttcttcttatgtctagtaatttggggttg

Downstream sequence

tatcctggacatggtcagtgaatgataaattggagaaactctgaactctgttatgttcttctcaagagtattaatttttgttgtagtagacagataactt