Basic Information
VIS ID
TVIS44022712
Fusion event
HTLV-1-SUGCT integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p14.1
Reference genome
GRCh37/hg19
Start
40456126/40416527 (Hg38)
End
40456126/40416527 (Hg38)
Orient
+
Location type
Intronic
Target gene
SUGCT
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-1183/Upstream/3497095; hsa-mir-10399/Downstream/2734368;
Nearest TSS
ENST00000635602/Upstream/142016; ENST00000460466/Downstream/130401;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/281108, chr7-CpG: 26/Downstream/1289053
Upstream sequence
ATAAATACTATATTTATtttcttccaatctgacttggaattcttattagaaaatatgcctgcattttatcaaattacttttagtaccatttatgaaatca
Downstream sequence
tagatatatagagatgtttctttaaggtttcaatgtaatgaatttgtcattatgtttattggtcatctttggctttctgaaataaactgtacctgatgac
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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