VISDB Viral Integration Site DataBase

VIS ID

TVIS44022733

Fusion event

HTLV-1-ZNF138 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr7

Cytoband

q11.21

Reference genome

Start

End

64285087/64824709 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-183-3p ; hsa-mir-4709-3p ; hsa-mir-143-5p ; hsa-mir-3944-5p ; hsa-mir-298 ; hsa-mir-5681a ; hsa-mir-6845-3p ; hsa-mir-455-5p ; hsa-mir-656-3p ; hsa-mir-296-3p ; hsa-mir-8087 ; hsa-mir-135b-3p ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-6754-3p ; hsa-mir-412-3p ; hsa-mir-3674 ; hsa-mir-629-3p ; hsa-mir-3925-3p ; hsa-mir-766-3p ; hsa-mir-770-5p ; hsa-mir-4712-5p ; hsa-mir-1-5p ; hsa-mir-4715-3p ; hsa-mir-3064-3p ; hsa-mir-23c ; hsa-mir-23b-3p ; hsa-mir-23a-3p ; hsa-mir-130a-5p ; hsa-mir-4732-5p ; hsa-mir-6832-5p ; hsa-mir-6837-3p ; hsa-mir-6509-3p ; hsa-mir-1257 ; hsa-mir-1273g-3p ; hsa-mir-181a-2-3p ; hsa-mir-200b-5p ; hsa-mir-200a-5p ; hsa-mir-4776-3p ; hsa-mir-7152-5p ; hsa-mir-3074-5p ; hsa-mir-4659b-5p ; hsa-mir-4659a-5p ; hsa-mir-5590-5p ; hsa-mir-19b-2-5p ; hsa-mir-19b-1-5p ; hsa-mir-19a-5p ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-3124-3p ; hsa-mir-1914-5p ; hsa-mir-570-5p ; hsa-mir-548ba ; hsa-mir-548ai ; hsa-mir-548ag ; hsa-mir-561-3p ; hsa-mir-548at-5p ; hsa-mir-3692-3p ; hsa-mir-2054 ; hsa-mir-511-3p ; hsa-mir-6867-3p ; hsa-mir-4713-5p ; hsa-mir-2355-5p ; hsa-mir-491-5p ; hsa-mir-193b-5p ; hsa-mir-5589-3p ; hsa-mir-4729 ; hsa-mir-135a-3p ; hsa-mir-648 ; hsa-mir-670-3p

Nearest miRNA

hsa-mir-1183/Upstream/145533; hsa-mir-10399/Downstream/2289613;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/30020, chr7-CpG: 35/Downstream/57569

Upstream sequence

tgctttctacatattggagccctgatgttgtacatgcacatacatagacaaatataatagttataaattcttgataaatttacccattttagtattacat

Downstream sequence

aatatcagtttttgtctcttgctagtactggacttaaagcatattatgtttaatataattatgacttcctcacgcaattgtggttactatttgcatagaa