Basic Information
VIS ID
TVIS44022734
Fusion event
HTLV-1-LOC105375330 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
64497652/65037274 (Hg38)
End
64497652/65037274 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7J
Target gene
LOC105375330
Nearest miRNA
hsa-mir-1183/Upstream/358098; hsa-mir-10399/Downstream/2077048;
Nearest TSS
ENST00000635602/Upstream/30531; ENST00000632111/Downstream/232100;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/89353, chr7-CpG: 93/Downstream/734
Nearby gene
CCT6P3(+1080) ;
Upstream sequence
agccaaatttatgatgcaattttaataactatgtaagcccctatggcctgcttatctgtgttcttattcctggcctttcattttattctgacttttcttt
Downstream sequence
ttcttcatcctgattgtattagctcatctttatttttctatattatatgagttatggtaagcaacttcaaattcagcttacggagaagcaaggcattcgt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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