Basic Information
VIS ID
TVIS44022764
Fusion event
HTLV-1-ZNF804B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q21.13
Reference genome
GRCh37/hg19
Start
88433794/88804480 (Hg38)
End
88433794/88804480 (Hg38)
Orient
+
Location type
Intronic
Target gene
ZNF804B
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-10525/Upstream/12889211; hsa-mir-10399/Downstream/3399535;
Nearest TSS
ENST00000635602/Upstream/8759; ENST00000611114/Downstream/413674;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/44511, chr7-CpG: 98/Downstream/1314098
Upstream sequence
ATGGAATACTGTATGGTATGCTTCGAAAATACCTTAAGATTGTCAGCTTCTATACAGAGATTTGGAGACTACATATAACACTAAACTCTCAGTTATGTTT
Downstream sequence
CTTTTATCTTCTTTTAATCAGTTTTTTTTCAGCTTCTTTGCAGGACAGAACACTAAAGCTTTATGACTTAACTAACACACAGTGCACATTATGATGAGGT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate