VISDB Viral Integration Site DataBase

VIS ID

TVIS44022765

Fusion event

HTLV-1-CLDN12 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr7

Cytoband

q21.13

Reference genome

Start

End

90042001/90412687 (Hg38)

Orient

-

Location type

Exonic

Target gene

miRNAs that regulate target gene

hsa-mir-125a-5p ; hsa-mir-30b-5p ; hsa-mir-1-3p ; hsa-mir-320b ; hsa-mir-320a ; hsa-mir-345-3p ; hsa-mir-670-5p ; hsa-mir-3140-5p ; hsa-mir-4263 ; hsa-mir-3667-5p ; hsa-mir-4680-3p ; hsa-mir-4744 ; hsa-mir-559 ; hsa-mir-548b-5p ; hsa-mir-548a-5p ; hsa-mir-548c-5p ; hsa-mir-548d-5p ; hsa-mir-548j-5p ; hsa-mir-548h-5p ; hsa-mir-548i ; hsa-mir-548w ; hsa-mir-548y ; hsa-mir-548o-5p ; hsa-mir-548ab ; hsa-mir-548ad-5p ; hsa-mir-548ae-5p ; hsa-mir-548ak ; hsa-mir-548am-5p ; hsa-mir-548ap-5p ; hsa-mir-548aq-5p ; hsa-mir-548ar-5p ; hsa-mir-548as-5p ; hsa-mir-548au-5p ; hsa-mir-548ay-5p ; hsa-mir-548bb-5p ; hsa-mir-142-3p ; hsa-let-7a-5p ; hsa-let-7b-5p ; hsa-let-7c-5p ; hsa-let-7d-5p ; hsa-let-7e-5p ; hsa-let-7f-5p ; hsa-mir-98-5p ; hsa-mir-224-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-mir-3927-3p ; hsa-mir-4458 ; hsa-mir-4500 ; hsa-mir-4650-3p ; hsa-mir-6831-5p ; hsa-mir-4760-3p ; hsa-mir-5197-3p ; hsa-mir-3622b-5p ; hsa-mir-202-3p ; hsa-mir-5693 ; hsa-mir-4719 ; hsa-mir-7856-5p ; hsa-mir-4477b ; hsa-mir-576-5p ; hsa-mir-4732-3p ; hsa-mir-6866-3p ; hsa-mir-188-5p ; hsa-mir-7161-5p ; hsa-mir-548u ; hsa-mir-4319 ; hsa-mir-125b-5p ; hsa-mir-676-5p ; hsa-mir-1294 ; hsa-mir-187-5p ; hsa-mir-206 ; hsa-mir-2467-5p ; hsa-mir-302b-5p ; hsa-mir-302d-5p ; hsa-mir-3120-3p ; hsa-mir-3188 ; hsa-mir-329-5p ; hsa-mir-3653-3p ; hsa-mir-3658 ; hsa-mir-377-5p ; hsa-mir-3975 ; hsa-mir-4316 ; hsa-mir-4457 ; hsa-mir-4461 ; hsa-mir-4703-3p ; hsa-mir-485-5p ; hsa-mir-507 ; hsa-mir-545-3p ; hsa-mir-557 ; hsa-mir-5585-5p ; hsa-mir-6086 ; hsa-mir-613 ; hsa-mir-655-5p ; hsa-mir-6716-5p ; hsa-mir-6783-5p ; hsa-mir-6884-5p ; hsa-mir-8066

Nearest miRNA

hsa-mir-10525/Upstream/14497418; hsa-mir-10399/Downstream/1791328;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/65974, chr7-CpG: 141/Downstream/183081

Upstream sequence

TGCTCTGTTCTGCTATTGTCCCCTCATGATTTGTCCTCTTGTGTGTCACCCCCTAGTCTGACTGACAGTACTCCACAAGCTTGCCTGCCATGGGCTGTCG

Downstream sequence

GGATGTCCACGCAGCCACAGTCCTTTCCTTCCTGTGTGGAATCGCCTCAGTAGCAGGCCTCTTTGCAGGGACTCTGCTTCCCAACTGGAGAAAATTACGA