Basic Information
VIS ID
TVIS44022799
Fusion event
HTLV-1-chr8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
115466703/114454474 (Hg38)
End
115466703/114454474 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-12123/Upstream/1810891; hsa-mir-10400/Downstream/2420254;
Nearest TSS
ENST00000518652/Upstream/172338; ENST00000415088/Downstream/1037747;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/1021618, chr8-CpG: 33/Downstream/1193731
Nearby gene
TRPS1(-954021) ;
Upstream sequence
gttgatgacaagcatgtaaacaaataaaaataacgtaatgcagaatagagagctataagagaagtacaaggacaggatgataAAATGAAAATTGTCCCCT
Downstream sequence
TACTACCTTTGAAATGCAAAAACAAACTTTGACTCTCGGAAAGACTTCTGCTCCattatttaaattaaaaataatGAGTTTAATTGAAACATCTGGTTTC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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