VISDB Viral Integration Site DataBase

VIS ID

TVIS44022826

Fusion event

HTLV-1-ARHGAP39 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr8

Cytoband

q24.3

Reference genome

Start

End

145768739/144543355 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-186-5p ; hsa-mir-3191-3p ; hsa-mir-92b-5p ; hsa-mir-24-3p ; hsa-mir-7154-3p ; hsa-mir-4756-3p ; hsa-mir-3919 ; hsa-mir-1179 ; hsa-mir-577 ; hsa-mir-3121-3p ; hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-185-5p ; hsa-mir-4533 ; hsa-mir-5004-5p ; hsa-mir-5681a ; hsa-mir-611 ; hsa-mir-3131 ; hsa-mir-9500 ; hsa-mir-4768-3p ; hsa-mir-4428 ; hsa-mir-1249-5p ; hsa-mir-1321 ; hsa-mir-149-3p ; hsa-mir-1908-5p ; hsa-mir-3928-5p ; hsa-mir-425-3p ; hsa-mir-4419a ; hsa-mir-4510 ; hsa-mir-4695-5p ; hsa-mir-4706 ; hsa-mir-4728-5p ; hsa-mir-4739 ; hsa-mir-4749-5p ; hsa-mir-4756-5p ; hsa-mir-6087 ; hsa-mir-6127 ; hsa-mir-6129 ; hsa-mir-6130 ; hsa-mir-6133 ; hsa-mir-663a ; hsa-mir-6731-5p ; hsa-mir-6760-5p ; hsa-mir-6785-5p ; hsa-mir-6787-5p ; hsa-mir-6796-3p ; hsa-mir-6797-5p ; hsa-mir-6806-3p ; hsa-mir-6877-5p ; hsa-mir-6883-5p ; hsa-mir-8085

Nearest miRNA

hsa-mir-10400/Upstream/80816; hsa-mir-6850/Downstream/248576;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/10047, chr8-CpG: 33/Downstream/2004

Upstream sequence

agccactgtgcctggcTGGGCCTGTCTTTCTGAGCAGCAGCCAGCACCTGCATGTGAAAGGGACACCTCCTAGGCACAGGAGGCTGGCTGGAGGGGGTGT

Downstream sequence

GAGGCTCATTTGGGAAGGAATGGCCACTGTGTATGTAGAGGCCTCTCTTCTGGGCTCAGGGCCAATCAGGGACCCTGACAGACGAACCTAGGAGTGGATC