Basic Information
VIS ID
TVIS44022839
Fusion event
HTLV-1-chr8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
23270248/23412735 (Hg38)
End
23270248/23412735 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/1167698; hsa-mir-10400/Downstream/1541061;
Nearest TSS
ENST00000518652/Upstream/8495; ENST00000521021/Downstream/12556;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/8381, chr8-CpG: 81/Downstream/44453
Nearby gene
LOXL2(-8526) ;
Upstream sequence
ggaggctgagatgggaggatagcttgatcccaggaggtgaagactgcagtgaactatgatgatgccattgcactccagcctgggcaacgtagcaagatcc
Downstream sequence
tatctctaaataaataaatgaaaTAggctgggtgcggtggctcacgcctgtaatcccagcactttgggaggccgagatgggcggatcacgaggtcaggag
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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