VISDB Viral Integration Site DataBase

VIS ID

TVIS44022840

Fusion event

HTLV-1-ENTPD4 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr8

Cytoband

p21.3

Reference genome

Start

End

23307974/23450461 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-122-5p ; hsa-mir-335-5p ; hsa-mir-484 ; hsa-let-7b-5p ; hsa-mir-548a-3p ; hsa-mir-548e-3p ; hsa-mir-548f-3p ; hsa-mir-548ar-3p ; hsa-mir-548az-3p ; hsa-mir-378a-5p ; hsa-mir-876-3p ; hsa-mir-3649 ; hsa-mir-323a-5p ; hsa-mir-6875-5p ; hsa-mir-3126-5p ; hsa-mir-4456 ; hsa-mir-6873-5p ; hsa-mir-582-3p ; hsa-mir-583 ; hsa-mir-335-3p ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-222-5p ; hsa-mir-644a ; hsa-mir-891a-3p ; hsa-mir-3688-5p ; hsa-mir-6513-3p ; hsa-mir-595 ; hsa-mir-433-3p ; hsa-mir-6778-3p ; hsa-mir-4707-3p ; hsa-mir-4454 ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-150-5p ; hsa-mir-7107-5p ; hsa-mir-1234-3p ; hsa-mir-186-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-17-5p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-106a-5p ; hsa-mir-5690 ; hsa-mir-6081 ; hsa-mir-3135b ; hsa-mir-6787-3p ; hsa-mir-1207-3p ; hsa-mir-6800-3p

Nearest miRNA

hsa-mir-124-1/Upstream/1205424; hsa-mir-10400/Downstream/1503335;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/46107, chr8-CpG: 81/Downstream/6727

Upstream sequence

ttgataaatgtctattagactgcccttttatgtacaaagtactgtgcaaggcactTTGTCCCTAGTCAGTTCTCCGACTCCACCATTATCACTCCTCCTC

Downstream sequence

CAGCCTCCAGGCCTCAAATTGCAGAGCAGACAGATGCCTTTAGCCAGGGCCTCCTTCCAATCTGCTGAAGCCAAAGGACAAGCGGTCTCTATCTTTCCTC