VISDB Viral Integration Site DataBase

VIS ID

TVIS44022848

Fusion event

HTLV-1-HMBOX1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr8

Cytoband

p21.1

Reference genome

Start

End

28800724/28943207 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-30c-1-3p ; hsa-mir-335-5p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106a-5p ; hsa-mir-187-5p ; hsa-mir-221-3p ; hsa-mir-222-3p ; hsa-mir-106b-5p ; hsa-mir-302a-3p ; hsa-mir-302b-3p ; hsa-mir-302c-3p ; hsa-mir-302d-3p ; hsa-mir-372-3p ; hsa-mir-373-3p ; hsa-mir-20b-5p ; hsa-mir-520e ; hsa-mir-520a-3p ; hsa-mir-526b-3p ; hsa-mir-520b ; hsa-mir-520c-3p ; hsa-mir-519d-3p ; hsa-mir-520d-3p ; hsa-mir-302e ; hsa-mir-548t-5p ; hsa-mir-548v ; hsa-mir-4501 ; hsa-mir-5580-3p ; hsa-mir-548az-5p ; hsa-mir-561-5p ; hsa-mir-6830-5p ; hsa-mir-802 ; hsa-mir-7-2-3p ; hsa-mir-7-1-3p ; hsa-mir-5688 ; hsa-mir-495-3p ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-548n ; hsa-mir-1238-3p ; hsa-mir-670-3p ; hsa-mir-3124-3p ; hsa-mir-342-3p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-6892-3p ; hsa-mir-216b-3p ; hsa-mir-8087 ; hsa-mir-7161-5p ; hsa-mir-548u ; hsa-mir-29b-2-5p ; hsa-mir-659-3p

Nearest miRNA

hsa-mir-124-1/Upstream/438025; hsa-mir-10400/Downstream/1014065;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/226884, chr8-CpG: 71/Downstream/128347

Upstream sequence

GAAAAAAATAGGTTGTTGTGTTTCACGCtgtaggggaggtaaaatttcttctgtgtccgtttagggtctctggctggacccaagaattaaactgatgtaa

Downstream sequence

gataaattaacaagagaaaaagcatacaaattgtattcaataatttacatgtacatgggagccctcacaagaaaatgaagacccaaggaagcagtgagga