Basic Information
VIS ID
TVIS44022870
Fusion event
HTLV-1-LOC105379397 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
p11.1
Reference genome
GRCh37/hg19
Start
43350963/43495820 (Hg38)
End
43350963/43495820 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105379397
Nearest miRNA
hsa-mir-124-1/Upstream/599545; hsa-mir-10400/Downstream/18218968;
Nearest TSS
ENST00000518652/Upstream/299652; ENST00000518278/Downstream/3326417;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/218485, chr8-CpG: 41/Downstream/3121547
Upstream sequence
gaggtagaaatctattagaaggatctgagcaggcaattgaATATGTGAGGAGTGGGGAGGTTTATTTGAGGTTCTGATAAAAAAGAGGAAAGACATTTTA
Downstream sequence
CACTCCAGCATTTTCCACCACTAGTGCCACCCACATACCGAATTTTTGGGACTTCAGTAGGTTGTTAAGCATTGTAAATGTATCAGGGGTTAATGAATAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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