VISDB Viral Integration Site DataBase

VIS ID

TVIS44022885

Fusion event

HTLV-1-LYN integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr8

Cytoband

q12.1

Reference genome

Start

End

56808864/55896305 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-222-3p ; hsa-mir-32-3p ; hsa-mir-4731-3p ; hsa-mir-4801 ; hsa-mir-548c-3p ; hsa-mir-205-5p ; hsa-mir-6513-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-4278 ; hsa-mir-625-5p ; hsa-mir-3148 ; hsa-mir-4668-5p ; hsa-mir-98-5p ; hsa-mir-4500 ; hsa-mir-4458 ; hsa-let-7i-5p ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-4330 ; hsa-mir-10b-3p ; hsa-mir-6732-5p ; hsa-mir-6805-5p ; hsa-mir-6794-5p ; hsa-mir-4716-3p ; hsa-mir-628-5p ; hsa-mir-466 ; hsa-mir-221-3p ; hsa-mir-548v ; hsa-mir-187-5p ; hsa-mir-4643 ; hsa-mir-4789-3p ; hsa-mir-122-5p ; hsa-mir-1304-3p ; hsa-mir-143-5p ; hsa-mir-3135b ; hsa-mir-3652 ; hsa-mir-4430 ; hsa-mir-4639-3p ; hsa-mir-504-3p ; hsa-mir-564 ; hsa-mir-5693 ; hsa-mir-5698 ; hsa-mir-6499-3p ; hsa-mir-6794-3p ; hsa-mir-891a-3p

Nearest miRNA

hsa-mir-124-1/Upstream/13000030; hsa-mir-10400/Downstream/5818483;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/15539, chr8-CpG: 69/Downstream/177692

Upstream sequence

gctgcagtgagctatgattatgccactgcactccagcctgggtagcagagcaagactctcatctctgaaaaaaaaagaaaagaaaaaGAAACAACAACAT

Downstream sequence

CAAACAAAGAAACAAAAGCAAGTTTATAAATAAAGAAACAGAATAgcagggacatggatgcagctggaaaccatcattctcagcaaactaacataagaac