Basic Information
VIS ID
TVIS44022896
Fusion event
HTLV-1-CPA6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
68387903/67475668 (Hg38)
End
68387903/67475668 (Hg38)
Orient
-
Location type
Intronic
Target gene
CPA6
miRNAs that regulate target gene
hsa-mir-124-3p
Nearest miRNA
hsa-mir-124-1/Upstream/3096411; hsa-mir-10400/Downstream/7072875;
Nearest TSS
ENST00000518652/Upstream/23018; ENST00000526382/Downstream/256919;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/131853, chr8-CpG: 64/Downstream/476522
Upstream sequence
CCTGGAGGCTTGTTTCAATGGCCACATGTGGTGGAGGCAGGGGATCAGTATTTGGGTTCTCAGTTTGCAGGAAAAGGGAGCAAGACCCAGACACACACCT
Downstream sequence
GGCAGTCTCAGAGCAGGACtctttcttttctttcctttccttcccttccttcccttctctttttttctttctttccttctttctttttttctttctttct
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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