Basic Information
VIS ID
TVIS44022901
Fusion event
HTLV-1-EYA1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
72300817/71388582 (Hg38)
End
72300817/71388582 (Hg38)
Orient
-
Location type
Intronic
Target gene
EYA1
miRNAs that regulate target gene
hsa-mir-562 ; hsa-mir-101-3p
Nearest miRNA
hsa-mir-124-1/Upstream/7009325; hsa-mir-10400/Downstream/3159961;
Nearest TSS
ENST00000518652/Upstream/26350; ENST00000521131/Downstream/159044;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/719167, chr8-CpG: 99/Downstream/158747
Nearby gene
EYA1(-26350) ;
Upstream sequence
TATTATCATGATGGCTAATGTGTAATTTCACATGTAGAAAGGAAGAGATCCGAGGACCTTTCTGGAACTATGACTCTACTCATCATTTCCAGGTAGCTTC
Downstream sequence
GATCTCAGCTGCCGGGGAGTAGAAACTAGAAAGAACAACCATATTATTCCATCTTCTAATTAATGCCACATTACACAAATAAAAACACAGAGCTCCTATG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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